Ultima Genomics, NVIDIA Use AI and Advanced Computing to Deliver $100 Genome Sequencing

$100 genome

PRESS RELEASE — Ultima Genomics, Inc. today unveiled a broad collaboration with NVIDIA that leverages AI-accelerated analysis across multiple stages of the DNA sequencing and analysis process. The collaboration includes the use of NVIDIA GPUs for deep learning in photometry and base calling and will soon include acceleration of variant calling.

Over the last five years, Ultima Genomics has developed a fundamentally new sequencing architecture designed to scale beyond conventional approaches, including completely different flow cell engineering, sequencing chemistry, and machine learning. Ultima is currently in an early access program for the UG 100™, its first high-throughput next-generation sequencing (NGS) instrument that is using this new technology, which enables customers to generate high-quality sequencing data at a cost of $1/Gb.

Genomics Meets AI

The Ultima instrument utilizes NVIDIA A30 GPUs with the NVIDIA Clara AI computing platform to offer highly accurate and accelerated primary and secondary analysis for customers who want to run genomic analyses at scale. Ultima has separately announced partnerships to develop Ultima-specific germline variant calling pipelines for Google’s DeepVariant. These custom models can be run within NVIDIA Clara Parabricks, which accelerates these and other applications for secondary analysis.

“Ultima’s mission is to continuously drive the scale of genomic information,” said Gilad Almogy, CEO of Ultima Genomics. “Our unique architecture scales by combining multiple technologies, so we are excited to work with NVIDIA, leveraging their platforms for GPUs and AI acceleration, to power high-quality sequencing and accelerate the computing to lower total cost of ownership for customers.”

“NVIDIA solutions are designed to accelerate high-volume data processing, and our collaboration with Ultima demonstrates this at multiple levels,” said George Vacek, Global Director of Genomics Alliances at NVIDIA.  “NVIDIA GPUs provide a high degree of onboard computational power within the UG 100, and data analysis can be accelerated downstream via Clara Parabricks, enabling large-scale data initiatives via analysis that is both higher throughput and lower cost.”

NVIDIA Clara Parabricks computational pipelines employ NVIDIA’s CUDA, HPC, AI and data analytics stacks to deliver GPU-accelerated libraries, pipelines, and reference application workflows for primary, secondary, and tertiary analysis. Off-the-shelf solutions are coupled with a toolkit to support new application development to address the rapidly evolving needs of high-throughput genomic labs.

About Ultima Genomics

Ultima Genomics is unleashing the power of genomics at scale. The Company’s mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. With humanity on the cusp of a biological revolution, there is a virtually endless need for more genomic information to address biology’s complexity and dynamic change—and a further need to challenge conventional next-generation sequencing technologies. Ultima’s revolutionary new sequencing architecture drives down the costs of sequencing to help overcome the tradeoffs that scientists and clinicians are forced to make between the breadth, depth, and frequency with which they use genomic information. The new sequencing architecture was designed to scale far beyond conventional sequencing technologies, lower the cost of genomic information and catalyze the next phase of genomics in the 21st century.

To learn more, visit www.ultimagenomics.com.